CAS NO: | 250694-07-6 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
Cas No. | 250694-07-6 |
别名 | 替格列卡 |
Canonical SMILES | O=C(N[C@H](CC([O-])=O)C[N+](C)(C)C)NCCCCCCCCCCCCCC |
分子式 | C22H45N3O3 |
分子量 | 399.61 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Teglicar is a selective and reversible inhibitor of liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1). Teglicar reduces ketogenesis and glucose production, decreases gluconeogenesis and improves glucose homeostasis. Teglicar has a potential antihyperglycemic propert[1]. IC50: L-CPT1[1] [1]. Conti R, et al. Selective reversible inhibition of liver carnitine palmitoyl-transferase 1 by teglicar reduces gluconeogenesis and improves glucose homeostasis. Diabetes. 2011 Feb;60(2):644-51. |