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Teglicar
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Teglicar图片
CAS NO:250694-07-6
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Teglicar 是选择性和可逆性的肉毒碱棕榈酰转移酶 1 (L-CPT1) 肝异构体抑制剂,可减少酮生成和葡萄糖生成,降低糖异生,改善葡萄糖稳态。Teglicar 具有潜在的抗高血糖特性。
Cas No.250694-07-6
别名替格列卡
Canonical SMILESO=C(N[C@H](CC([O-])=O)C[N+](C)(C)C)NCCCCCCCCCCCCCC
分子式C22H45N3O3
分子量399.61
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Teglicar is a selective and reversible inhibitor of liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1). Teglicar reduces ketogenesis and glucose production, decreases gluconeogenesis and improves glucose homeostasis. Teglicar has a potential antihyperglycemic propert[1]. IC50: L-CPT1[1]

[1]. Conti R, et al. Selective reversible inhibition of liver carnitine palmitoyl-transferase 1 by teglicar reduces gluconeogenesis and improves glucose homeostasis. Diabetes. 2011 Feb;60(2):644-51.