化学性质
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 218.25 |
Cas No. | 77472-70-9 |
Formula | C12H14N2O2 |
Synonyms | Phenotropyl;Phenotropil;Carphedon;Fonturacetam;Karfedon |
Solubility | ≥10.92 mg/mL in DMSO; ≥18.5 mg/mL in H2O with gentle warming and ultrasonic; ≥58.2 mg/mL in EtOH with gentle warming |
Chemical Name | 2-(2-oxo-4-phenylpyrrolidin-1-yl)acetamide |
Canonical SMILES | O=C1N(CC(N)=O)CC(C2=CC=CC=C2)C1 |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
资料参考
Description:
IC50 Value: N/A
Phenylpiracetam is a phenylated derivative of the nootropic drug piracetam. It is used as astimulant nootropic drug that can be up to 30-60 times more potent than piracetam.
in vitro: N/A
in vivo: In the open-field test, a significant increase in locomotor activity was observed after a single administration of R-phenotropil at doses of 10 and 50 mg/kg and S-phenotropil at a dose of 50 mg/kg. In the forced swim test, R-phenotropil induced an antidepressant effect at doses of 100 and 50 mg/kg, and S-phenotropil was active at a dose of 100 mg/kg. R-phenotropil significantly enhanced memory function in a passive avoidance response test at a dose of 1 mg/kg; the S-enantiomer did not show any activity in this test [1].
Toxicity: N/A
Clinical trial: N/A