化学性质
Physical Appearance | A white to off-white solid |
Storage | Store at 4°C |
M.Wt | 183.16 |
Cas No. | 72835-26-8 |
Formula | C8H9NO4 |
Solubility | Soluble in DMSO |
Chemical Name | (2,5-dioxopyrrol-1-yl)methyl propanoate |
Canonical SMILES | CCC(=O)OCN1C(=O)C=CC1=O |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
资料参考
Restores wild-type conformation, function and DNA binding activity to mutant p53. Induces p53 transcriptional transactivation of p21, MDM2 and PUMA, and promotes tumor cell death by apoptosis in a mutant p53-dependent mannerin vitro(IC50= 10μM).