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FM-red
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
FM-red图片
包装与价格：
包装价格(元)
5mg电议
10mg电议

产品介绍
FM-red(PSH-red)是一种发红光且对环境敏感的探针，用于选择性检测和标记蛋白硫醇。FM-red可用于在活细胞和体内蛋白质巯基的成像。FM-red也可用于测量硫氧还蛋白(Trx)的氧化还原状态。
别名PSH-red
Canonical SMILESCN(C1=CC=C(C2=[O+]C3=C(C=CC(N(CC)CC)=C3)C(C4=C(C=CC=C4)C(N5CCC(CC5)NC(CCCN6C(C=CC6=O)=O)=O)=O)=C2)C=C1)C.O=Cl(=O)([O-])=O
分子式C41H46ClN5O9
分子量788.29
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

FM-red (PSH-red) is a red-emitting and environment-sensitive probe for selectively detecting and labeling protein thiols. FM-red can be used to image protein sulfhydryl groups in live cells and in vivo. FM-red also could be used to measure of the redox states of thioredoxin (Trx)[1].

FM-red (10 μM; 30 min) is suitable for imaging protein thiols in HeLa cells[1].FM-red (20 μM; 48 h) has no significant cytotoxicity in HeLa cells[1].FM-red possesses a long emission wavelength (~655 nm) and fast response (~10 min) by binding to protein thiols[1].FM-red exhibits time- and concentration-dependent fluorescence response to bovine serum albumin (BSA)[1].

FM-red (10 μM; 30 min) could be used to image protein thiols in zebrafishes[1].

[1]. Hu G, et, al. Depletion of protein thiols and the accumulation of oxidized thioredoxin in Parkinsonism disclosed by a red-emitting and environment-sensitive probe. J Mater Chem B. 2019 Apr 28;7(16):2696-2702.