Fluo-3AM(Fluo-3-pentaacetoxymethyl ester)是一种钙指示剂,在结合 Ca2+ 时会增加荧光;用于对 Ca2+ 信号传导的空间动力学进行成像,在涉及光激活笼状螯合剂、第二信使和神经递质的流式细胞术实验中,以及用于基于细胞的药理学筛选。
Cas No. | 121714-22-5 |
别名 | 钙荧光探针Fluo3-AM,Fluo-3-pentaacetoxymethyl ester |
Canonical SMILES | ClC(C=C1C(C2=CC(OCCOC(C=C(C)C=C3)=C3N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)=C(N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C=C2)=C(C=C4Cl)C5=CC4=O)=C(C=C1O5)OCOC(C)=O |
分子式 | C51H50Cl2N2O23 |
分子量 | 1129.85 |
溶解度 | Acetonitrile: 2 mg/ml,DMSO: 0.9 mg/ml |
储存条件 | Store at -20℃,protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Fluo-3AM(Fluo-3-pentaacetoxymethyl ester) is a calcium indicator that exhibit an increase in fluorescence upon binding Ca2+; used to image the spatial dynamics of Ca2+ signaling, in flow cytometry experiments involving photoactivation of caged chelators, second messengers, and neurotransmitters, and for cell-based pharmacological screening. |