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Fast-TRFS
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Fast-TRFS图片
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
Fast-TRFS是硫氧还蛋白还原酶(TrxR)的选择性超快荧光探针。Fast-TRFS可用于对活细胞中的TrxR活性进行成像。
Canonical SMILESO=C1OC(C=C(C=C2)NC(NC3CSSC3)=O)=C2C(C(F)(F)F)=C1
分子式C14H11F3N2O3S2
分子量376.37
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Fast-TRFS is a selective and superfast fluorogenic probe of thioredoxin reductase (TrxR). Fast-TRFS can be used for imaging TrxR activity in live cells[1].

Fast-TRFS reaches the maximal fluorescence signal within 1 min incubated with TCEP, and within 5 min incubated with the TrxR enzyme[1].Fast-TRFS (10 μM; 2-60 min) appears the blue fluorescence signal within 2 min in HeLa cells[1].

[1]. Li X, et, al. A fast and specific fluorescent probe for thioredoxin reductase that works via disulphide bond cleavage. Nat Commun. 2019 Jun 21;10(1):2745.