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Flunisolide
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Flunisolide图片
CAS NO:3385-03-3
包装:100mg
市场价:2880元

产品介绍

Flunisolide是一种皮质类固醇,常用于治疗过敏性鼻炎。Flunisolide的主要作用机制是激活糖皮质激素受体,意味着它具有抗炎作用。

Cas No.3385-03-3
别名氟尼缩松
Canonical SMILESC[C@@]12[C@@]3(C(CO)=O)[C@@](OC(C)(O3)C)([H])C[C@@]1([H])[C@]4([H])C[C@H](F)C5=CC(C=C[C@]5(C)[C@@]4([H])[C@@H](O)C2)=O
分子式C24H31FO6
分子量434.5
溶解度30mg/ml in ethanol or DMSO, or DMF
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Flunisolide is a fluorinated corticosteroid receptor agonist that induces reversible pyloric hyalinization in CD-1 mice following oral administration at a dose of 200 μg/kg per day.[1] Formulations containing flunisolide have been used for the treatment of asthma.[2]

Reference:
[1]. McKevitt, T.P., Giffen, P., Woodfine, J.A., et al. Hyalinization of the pyloric stomach in CD-1 mice following oral (dietary) administration of the corticosteroid agonists mometasone furoate, budesonide, and flunisolide. Toxicol. Pathol. 39(6), 958-968 (2011).
[2]. O'Callaghan, C., White, J.A., and Kantar, A. Nebulization of corticosteroids to asthmatic children: Large variation in dose inhaled. Respirology 19(2), 276-279 (2014).