| CAS NO: | 5003-48-5 |
| 包装 | 价格(元) |
| 10mM (in 1mL DMSO) | 电议 |
| 100mg | 电议 |
| Cas No. | 5003-48-5 |
| 别名 | 贝诺酯; Salipran |
| Canonical SMILES | O=C(OC1=CC=C(NC(C)=O)C=C1)C2=CC=CC=C2OC(C)=O |
| 分子式 | C17H15NO5 |
| 分子量 | 313.3 |
| 溶解度 | DMSO : 125 mg/mL (398.98 mM) |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Benorylate (Benoral) is the esterification product of paracetamol and acetylsalicylic acid. It has anti-inflammatory, analgesic and antipyretic properties. Benorylate could also inhibit prostaglandin (PG) synthesis. Benorilate is an esterified aspirin preparation whose antirheumatic properties are reported to be as good as those of aspirin[1]. Benorylate causes a large decrease in the liver's conversion rate of lactate into glucose, an important component of glucose homeostasis. Benorylate also impairs the urea synthesis rate from ammonia, another important function of the liver[2]. Benorylate is probably absorbed as the intact molecule which accounts for its good gastric tolerance[3]. Benorylate could inhibit PG synthesis in laboratory animals and in human tissue[4]. [1]. Croft DN, et al. Gastric bleeding and benorylate, a new aspirin. Br Med J. 1972 Sep 2;3(5826):545-7. [2]. Castell JV, et al. Effects of benorylate and impacina on the metabolism of cultured hepatocytes. Xenobiotica. 1985 Aug-Sep;15(8-9):743-9. [3]. Wright V, et al. A review of benorylate - a new antirheumatic drug. Scand J Rheumatol Suppl. 1975;13:5-8. [4]. A. Bennett , et al. Inhibition of Prostaglandin Synthesis by Benorylate. Rheumatology, Volume XII, Issue suppl, 1 January 1973, Pages 101-105. |
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