CAS NO: | 1010073-75-2 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
20mg | 电议 |
Cas No. | 1010073-75-2 |
Canonical SMILES | COC1=CC(N2CCN(C(CN3N=C(C4=NC=CN4)C5=CC=CN=C53)=O)CC2)=CC=C1Cl |
分子式 | C22H22ClN7O2 |
分子量 | 451.91 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | CCR1 antagonist 1 is an antagonist of CCR1, with anti-inflammatory activity. CCR1 antagonist 1 shows potent activities in the chemotaxis assay, with IC50< 100 nM[1]. In vivo, CCR1 antagonist 1 has in vivo anti-inflammatory activity and has superior pharmacokinetic properties[1]. [1]. Compounds for the treatment of osteoporosis and cancers. US 20100113472 A1 |