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CCR1 antagonist 1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CCR1 antagonist 1图片
CAS NO:1010073-75-2
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
CCR1 拮抗剂 1 是 CCR1 的拮抗剂,具有抗炎活性。
Cas No.1010073-75-2
Canonical SMILESCOC1=CC(N2CCN(C(CN3N=C(C4=NC=CN4)C5=CC=CN=C53)=O)CC2)=CC=C1Cl
分子式C22H22ClN7O2
分子量451.91
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

CCR1 antagonist 1 is an antagonist of CCR1, with anti-inflammatory activity.

CCR1 antagonist 1 shows potent activities in the chemotaxis assay, with IC50< 100 nM[1].

In vivo, CCR1 antagonist 1 has in vivo anti-inflammatory activity and has superior pharmacokinetic properties[1].

[1]. Compounds for the treatment of osteoporosis and cancers. US 20100113472 A1