Atractylone

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Atractylone

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

6989-21-5

包装与价格：

包装	价格(元)
1mg	电议
5mg	电议

产品介绍

Atractylone (Atractylon) 是从苍术中提取的一种倍半萜。Atractylone (Atractylon) 通过调节 TLR7 信号通路，减轻甲型流感病毒 (IAV) 诱导的肺损伤，有前景成为治疗 IAV 的药物。Atractylone (Atractylon) 能抑制肥大细胞脱粒，具有治疗肥大细胞介导的过敏反应的潜力。

Cas No.	6989-21-5
别名	苍术酮
Canonical SMILES	C=C1[C@]2([H])CC3=C(C[C@@]2(C)CCC1)OC=C3C
分子式	C₁₅H₂₀O
分子量	216.32
溶解度	Soluble in DMSO
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	Atractylone (Atractylon) is a sesquiterpenoid extracted from Atractylodis Rhizoma. Atractylone (Atractylon) alleviates influenza A virus (IAV)-induced lung injury via regulating the TLR7 signaling pathway, and acts as a promising agent for IAV treatment. Atractylone (Atractylon) inhibits the degranulation of mast cell and exhibits potential for the treatment of mast cell-mediated allergic reactions[1][2]. [1]. Cheng Y, et al. Antiviral activities of atractylon from Atractylodis Rhizoma. Mol Med Rep. 2016 Oct;14(4):3704-10. [2]. Han NR, et al. Inhibitory effects of atractylone on mast cell-mediated allergic reactions. Chem Biol Interact. 2016 Oct 25;258:59-68.