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Dexrazoxane HCl(ICRF-187,ADR-529)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Dexrazoxane HCl(ICRF-187,ADR-529)图片
CAS NO:149003-01-0
包装与价格：
包装价格(元)
10mg电议
50mg电议
100mg电议

产品介绍
Topoisomerase II inhibitor,intracellular ion chelator,cardioprotective agent
Cas No.149003-01-0
别名右雷佐生盐酸盐; ICRF-187 hydrochloride; ADR-529 hydrochloride; NSC-169780 hydrochloride
化学名4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione;hydrochloride
Canonical SMILESCC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2.Cl
分子式C11H16N4O4.HCl
分子量304.73
溶解度≥ 15.24mg/mL in DMSO
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dexrazoxane hydrochloride (ICRF-187 hydrochloride) is a cardioprotective agent.

References:
[1]. Hasinoff BB. The use of dexrazoxane for the prevention of anthracycline extravasation injury. Expert Opin Investig Drugs. 2008 Feb;17(2):217-23.
[2]. Jones RL. Utility of dexrazoxane for the reduction of anthracycline-induced cardiotoxicity. Expert Rev Cardiovasc Ther. 2008 Nov;6(10):1311-7.
[3]. Lipshultz SE, Scully RE, Lipsitz SR et al. Assessment of dexrazoxane as a cardioprotectant in doxorubicin-treated children with high-risk acute lymphoblastic leukaemia: long-term follow-up of a prospective, randomised, multicentre trial. Lancet Oncol. 2010 Oct;11(10):950-61.