Clindamycin sulfoxide is an active metabolite of the antibiotic clindamycin.
Cas No. | 22431-46-5 |
别名 | 克林霉素亚砜 |
Canonical SMILES | O=C(N[C@@]([C@H](C)Cl)([H])[C@@]1([H])O[C@@](S(C)=O)([H])[C@H](O)[C@@H](O)[C@H]1O)[C@H]2N(C)C[C@H](CCC)C2 |
分子式 | C18H33ClN2O6S |
分子量 | 441 |
溶解度 | Methanol: Slightly Soluble,Water: Slightly Soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Clindamycin sulfoxide is an active metabolite of the antibiotic clindamycin . It is formed via S-oxidation of clindamycin primarily by the cytochrome P450 (CYP) isoform CYP3A4. Clindamycin sulfoxide inhibits the growth of P. prevotti, B. fragilis, and C. sordelli in vitro with MIC values of 2, 2, and 1 mg/L, respectively. |