Dehydro nifedipine is an active metabolite of nifedipine, a calcium channel blocker present in formulations used to treat hypertension and angina.
| Cas No. | 67035-22-7 |
| 别名 | 4-(2硝基苯基)-2,6-二甲基吡啶-3,5二羧酸二甲酯 |
| Canonical SMILES | CC1=C(C(OC)=O)C(C2=CC=CC=C2[N+]([O-])=O)=C(C(OC)=O)C(C)=N1 |
| 分子式 | C17H16N2O6 |
| 分子量 | 344.3 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml,Ethanol: 3 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Dehydro nifedipine is an active metabolite of nifedipine , a calcium channel blocker present in formulations used to treat hypertension and angina. Dehydro nifedipine is formed when nifedipine is metabolized by the cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5. Dehydro nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM. |
m.cnreagent.com