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Glucagon Receptor Antagonist I
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Glucagon Receptor Antagonist I图片
CAS NO:438618-32-7
包装与价格：
包装价格(元)
500μg电议
1mg电议
5mg电议

产品介绍
Cas No.438618-32-7
Canonical SMILESO=C(C(CC)CC)NC(S1)=C(C#N)C2=C1CC(C(C)(C)CC)CC2
分子式C20H30N2OS
分子量346.5
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Glucagon receptor antagonist I is a competitive antagonist of the glucagon receptor (GCGR; IC50 = 181 nM). It blocks glucagon-induced glycogenolysis in primary human hepatocytes and isolated liver. Glucagon receptor antagonist I, at 50 mg/kg, reduces the increase in glucose levels observed after intraperitoneal administration of glucagon in humanized mice. Glucagon receptor antagonist inactive control does not prevent glucagon-mediated actions.