Zerumbone

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Zerumbone

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

471-05-6

包装与价格：

包装	价格(元)
5mg	电议
10mg	电议
50mg	电议

产品介绍

化学性质

Physical Appearance	A solid
Storage	Store at -20°C
M.Wt	218.33
Cas No.	471-05-6
Formula	C₁₅H₂₂O
Solubility	insoluble in H2O; ≥44.4 mg/mL in EtOH; ≥81.4 mg/mL in DMSO
Chemical Name	(2Z,6E,10E)-2,6,9,9-tetramethylcycloundeca-2,6,10-trienone
Canonical SMILES	C/C1=C/CC/C(C)=C/CC(C)(C)/C=C/C1=O
运输条件	蓝冰运输或根据您的需求运输。
一般建议	为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。

资料参考

Zerumbone is a sesquiterpene isolated from in Zingiber zerumbet Smith (wild ginger),which exhibits antitumor activity[1].Zerumbone is a TRAIL-induced apoptosis potentiator. It potentiates TRAIL-induced apoptosis through the up-regulation of DR4 and DR5 expression and the down-regulation of cFLIP. Zerumbone has very little or no cytotoxic effect on the normal human endothelial cells and dermal fibroblasts.

参考文献：
[1]Kamalidehghan B, Ahmadipour F, Noordin M I. DNA Fragmentation Is Not Associated with Apoptosis in Zerumbone-induced HepG2 Cells[J]. Iranian Biomedical Journal, 2012, 16(4):226.