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Dopastin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dopastin图片
CAS NO:37134-80-8
包装:1mg
市场价:7031元

产品介绍
A bacterial metabolite and an inhibitor of dopamine β-hydroxylase
Cas No.37134-80-8
别名制多巴素
Canonical SMILESO=C(NC[C@@H](N(N=O)O)C(C)C)/C=C/C
分子式C9H17N3O3
分子量215.3
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dopastin is a bacterial metabolite that has been found inPseudomonasand an inhibitor of dopamine β-hydroxylase (Ki= 4.7 µM).1,2In vivo, dopastin (20 mg/kg) reduces mean systolic blood pressure in spontaneously hypertensive rats. Dopastin also inhibits the germination of barley seeds (IC50= 47 µM).2

1.Iinuma, H., Takeuchi, T., Kondo, S., et al.Dopastin, an inhibitor of dopamine β-hydroxylaseJ. Antibiot. (Tokyo)25(8)497-500(1972) 2.Iinuma, H., Matsuzaki, M., Nagatsu, T., et al.Biochemical and biological studies on dopastin, an inhibitor of dopamine β-hydroxylaseAgric. BioI. Chem.38(11)2107-2111(1974)