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Docosahexaenoic Acid ethyl ester
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Docosahexaenoic Acid ethyl ester图片
CAS NO:81926-94-5
包装与价格：
包装价格(元)
50mg电议
100mg电议
500mg电议
1g电议

产品介绍
二十二碳六烯酸乙酯 (Ethyl docosahexaenoate) 是一种 90% 浓缩的二十二碳六烯酸乙酯，由微藻油制成。
Cas No.81926-94-5
别名(4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,16,19-二十二碳六烯酸乙酯,Ethyl docosahexaenoate
Canonical SMILESCC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(OCC)=O
分子式C24H36O2
分子量356.5
溶解度DMF: 100 mg/ml,DMSO: 100 mg/ml,Ethanol: 500 mg/ml,PBS (pH 7.2): 0.15 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Fish oils in the diet have anti-inflammatory and cardiovascular benefits due to an abundance of ω-3 polyunsaturated fatty acids (PUFAs), including docosahexaenoic acid (DHA).1 DHA is the most abundant ω-3 PUFA in neural tissues, especially in the retina and brain. DHA ethyl ester is the stabilized ethyl ester form of the ω-3 22:6 fatty acid. Dietary intake of DHA ethyl ester enhances maze-learning ability in old mice.2 In rats, dietary DHA ethyl ester increases plasma and erythrocyte membrane DHA levels without altering the content of the ω-6 arachidonic acid.3 Dietary DHA ethyl ester increases fatty acid oxidation enzymes in rats and, in humans with peroxisomal disorders, improves vision, liver function, muscle tone, and social contact.4,5 The ω-3 fatty acid eicosapentaenoic acid competitively inhibits the metabolism of arachidonic acid by COX enzymes, suggesting that DHA ethyl ester may also directly modulate the actions of enzymes involved in fatty acid metabolism.6

References
1. von Schacky, C. A review of omega-3 ethyl esters for cardiovascular prevention and treatment of increased blood triglyceride levels. Vascular Health and Risk Management 2(3), 251-262 (2006).
2. Lim, S.Y., and Suzuki, H. Intakes of dietary docosahexaenoic acid ethyl ester and egg phosphatidylcholine improve maze-learning ability in young and old mice. Journal of Nutrition 130, 1629-1632 (2000).
3. Valenzuela, A., Valenzuela, V., Sanhueza, J., et al. Effects of supplementation with docosahexaenoic acid ethyl ester and sn-2 docosahexaenyl monoacylglyceride on plasma and erythrocyte fatty acids in rats. Annuals of Nutrition and Metabolism 49, 49-53 (2005).
4. Hong, D.D., Takahashi, Y., Kushiro, M., et al. Divergent effects of eicosapentaenoic and docosahexaenoic acid ethyl esters, and fish oil on hepatic fatty acid oxidation in the rat. Biochimica et Biophysica Acta 1635, 29-36 (2003).
5. Martinez, M., VÁzquez, E., GarcÍa-Silva, M.T., et al. Therapeutic effects of docosahexaenoic acid ethyl ester in patients with generalized peroxisomal disorders. American Journal of Clinical Nutrition 71, 376S-385S (2000).
6. Wada, M., DeLong, C.J., Hong, Y.H., et al. Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products. J. Biol. Chem. 282(31), 22254-22266 (2007).