化学性质
Physical Appearance | A solid |
Storage | Desiccate at RT |
M.Wt | 146.15 |
Cas No. | 491-36-1 |
Formula | C8H6N2O |
Solubility | ≥7.4 mg/mL in DMSO; insoluble in H2O; ≥4.55 mg/mL in EtOH with gentle warming and ultrasonic |
Chemical Name | 1H-quinazolin-4-one |
Canonical SMILES | C1=CC=C2C(=C1)C(=O)N=CN2 |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
资料参考
Inhibitor of poly(ADP-ribose) polymerase (PARP) (IC50 = 9.5 μM); displays mixed inhibition with respect to NAD+. Protective against ischemia-reperfusion induced ROS production, and subsequent mitochondrial and cell damage in rat heart. Anti-inflammatory in LPS-induced endotoxic mice in vivo; decreases NF-κB and AP-1 activation.