| CAS NO: | 23109-05-9 |
| 包装: | 1mg |
| 市场价: | 2394元 |
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 918.97 |
| Cas No. | 23109-05-9 |
| Formula | C39H54N10O14S |
| Solubility | ≥1 mg/mL in H2O; Soluble in Ethanol |
| Canonical SMILES | CCC(C)C1C(=O)NCC(=O)NC2CS(=O)C3=C(CC(C(=O)NCC(=O)N1)NC(=O)C(NC(=O)C4CC(CN4C(=O)C(NC2=O)CC(=O)N)O)C(C)C(CO)O)C5=C(N3)C=C(C=C5)O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
| Cell experiment:[1] | |
Cell lines | Mouse blastocysts |
Reaction Conditions | 1.1 μg/ml α-amanitin |
Applications | α-Amanitin inhibited the incorporation of3H-UMP into embryos. α-Amanitin at the concentration of 1.1 μg/ml was found to inhibit RNA polymerase activity by 32%. |
| Animal experiment:[1] | |
Animal models | Preimplantation mouse embryos at the two-cell stage of development collected from CF1 female mice |
Dosage form | 0 ~ 1 μg/ml α-amanitin 48 h |
Applications | Less than 1% of the embryos which had been treated with 1 μg/ml of α-amanitin developed to the morula or blastocyst stages. α-Amanitin can be used to determine which forms of RNA polymerase are active and the relative amounts of each form which are present in preimplantation mouse embryos. |
Note | The technical data provided above is for reference only. |
References: 1. Warner CM, Versteegh LR. In vivo and in vitro effect of alpha-amanitin on preimplantation mouse embryo RNA polymerase. Nature, 1974, 248(5450): 678-680. | |
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