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Etersalate(Eterylate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Etersalate(Eterylate)图片
CAS NO:62992-61-4
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
Etersalate (Eterylate) 抑制血小板功能并降低血栓素 A2 (TXA2) 水平。
Cas No.62992-61-4
别名依特柳酯,Eterylate; Etherylate
Canonical SMILESO=C(OCCOC1=CC=C(NC(C)=O)C=C1)C2=CC=CC=C2OC(C)=O
分子式C19H19NO6
分子量357.36
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Etersalate inhibits platelet function and decreases thromboxane A2 (TXA2) levels.

Ex vivo antiplatelet properties of Etersalate and its effects on serum thromboxane A2 (TXA2) levels and prostaglandin I2 (PGI2) generation are studied in human volunteers at two levels of oral dosing. Etersalate inhibits at the lower dosage platelet function and decreased TXA2 levels, but PGI2 generation from rat aortic rings is stimulated when incubated with plasma from Etersalate-treated donors. Blood coagulation parameters remain within normal values. Etersalate administration can act on platelet arachidonate metabolism at a different level than that of the cyclooxygenase pathway[1].

[1]. Ortega MP, et al. Effect of etersalate on human platelet responsiveness. A study in healthy volunteers. Arzneimittelforschung. 1987 Feb;37(2):214-7.