| CAS NO: | 13292-46-1 |
| 包装 | 价格(元) |
| 10mM (in 1mL DMSO) | 电议 |
| 1g | 电议 |
| 5g | 电议 |
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 822.94 |
| Cas No. | 13292-46-1 |
| Formula | C43H58N4O12 |
| Solubility | ≥26.25 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH |
| Canonical SMILES | O[C@H]([C@H](C)[C@H]([C@H](/C=C/C=C(C)/C(NC1=C2O)=O)C)O)[C@@H](C)[C@@H]([C@H](C)[C@H](/C=C/O[C@@]3(C)OC4=C(C)C(O)=C2C(C(/C1=C/NN5CCN(C)CC5)=O)=C4C3=O)OC)OC(C)=O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
| Animal experiment:[1] | |
Animal models | Male Parkes strain mice (20 ~ 25g) inoculated in the left hind footpad with 1 × 104viable units ofMycobacterium marinum(M. marinum) |
Dosage form | 0.003%, 0.01%, 0.03% and 0.1% rifampin in the diet Administered by oral route |
Applications | Rifampin at dosages of 0.003% and 0.01% in the diet was not suppressive to bacillary growth. A dosage of 0.03% resulted in a transient fall in viable bacillary count, which was followed by recovery of growth 10 days after inoculation. The highest dose (0.1%) was highly bactericidal, with the viable count ofM. marinumreduced to, and maintained below, the detectable level of 2.0 × 102organisms per foot pad after 7 days of treatment. |
Note | The technical data provided above is for reference only. |
References: 1. Banerjee DK, Holmes IB. In vitro and in vivo studies of the action of rifampicin, clofazimine and B1912 on Mycobacterium marinum. Chemotherapy, 1976, 22(3-4): 242-252. | |
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