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Schisandrol B
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Schisandrol B图片
CAS NO:58546-54-6
包装:20mg
市场价:1533元

产品介绍
Schisandrol B (Gomisin-A) 是华中五味子的主要活性成分，具有保肝作用。 Schisandrol B 抑制活性氧 (ROS) 的产生。 Schisandrol B 抑制 P-糖蛋白和 CYP3A 的活性，还具有抗炎、抗糖尿病和抗氧化活性。
Cas No.58546-54-6
别名五味子醇乙; Gomisin-A; TJN-101; Wuweizi alcohol-B
化学名(6R,7R)-1,2,3,13-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol
Canonical SMILES[H][C@](C([H])([H])C(C1=C2OC([H])([H])[H])=C([H])C3=C2OC([H])([H])O3)(C([H])([H])[H])[C@](C([H])([H])C(C1=C4OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C4OC([H])([H])[H])(C([H])([H])[H])O[H]
分子式C23H28O7
分子量416.47
溶解度≥ 41.6mg/mL in DMSO
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Schisandrol B (Gomisin-A;TJN-101;Wuweizi alcohol-B) is one of its major active constituents of traditional hepato-protective Chinese medicine, Schisandra sphenanthera.

References:
[1]. Jiang Y, et al. Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration. Toxicol Sci. 2015 Jan;143(1):107-15.
[2]. Jin J, et al. Enhancement of oral bioavailability of paclitaxel after oral administration of Schisandrol B in rats. Biopharm Drug Dispos. 2010 May;31(4):264-8.