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Polyphyllin VII
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Polyphyllin VII图片
CAS NO:76296-75-8
包装:20mg
市场价:3129元

产品介绍
Polyphyllin VII 是从云南巴黎的根茎中分离得到的，具有抗菌和抗癌活性。
Cas No.76296-75-8
别名重楼皂苷G
化学名Polyphyllin VII
分子式C51H84O22
分子量1049.2
溶解度≥ 82.3mg/mL in DMSO
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Polyphyllin G is isolated from the rhizomes of Paris yunnanensis, with antimicrobial and anticancer activity. Polyphyllin G prevents the growth of both Gram-positive and Gram-negative bacteria with minimum inhibitory concentrations (MICs)[1].Polyphyllin G induces apoptosis dependent on the activations of caspase-8, -3, and -9, induces autophagy[2].

References:
[1]. Cai X, et al. Polyphyllin G exhibits antimicrobial activity and exerts anticancer effects on human oral cancer OECM-1 cells by triggering G2/M cell cycle arrest by inactivating cdc25C-cdc2. Arch Biochem Biophys. 2018 Apr 15;644:93-99.
[2]. Hsieh MJ, et al. Polyphyllin G induces apoptosis and autophagy cell death in human oral cancer cells. Phytomedicine. 2016 Dec 1;23(13):1545-1554.