| 包装 | 价格(元) |
| 5ug | 电议 |
| 50ug | 电议 |
| 500ug | 电议 |
| Gene ID: | 7040 | Accession #: | P01137 |
| Alternate Names: | TGFB1, Human TGF-beta1, TGF-beta1, TGF beta1, TGFbeta1, h-TGF-beta1, rh-TGF-beta1, recombinant human TGF-beta1, recombinant TGF-beta, TGF. | ||
| Source: | CHO cells. | M.Wt: | 25.0 kDa |
| Appearance: | Lyophilized protein | Storage: | Store at -20°C |
| Formulation: | Lyophilized from Sodium Citrate, pH3.5 buffer. | ||
| Solubility: | Reconstitution in water to a concentration of 50 ug/ml (e.g., 5 ug/100 ul) will yield a solution of 1 mM citrate buffer (pH 3.5). The solution can then be stored at 4°C for 1 month. It is recommended that further dilutions be made in PBS containing 2 mg/ml albumin and stored at -20℃. | ||
| Shipping Condition: | Gel pack. | Handling: | Centrifuge the vial prior to opening. |
| Usage: | For Research Use Only! Not to be used in humans. | ||
Transforming Growth Factor-β1 (TGF-β1) is a pleiotropic cytokine mainly produced by platelets and bone, and regulates cell proliferation, growth, differentiation and motility. TGF-β1 is involved in embryogenesis, tissue remodeling, wound healing, hematopoiesis and endothelial differentiation.
The human TGF-β1 cDNA encodes a 390 aa dimeric inactive precursor protein, which is cleaved to an active dimer of 112 residues disulphide-linked peptides. Recombinant human TGF-β1 is a 25.0 kDa protein containing two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
| Determined by the ability of TGF-β1 to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. | ||||||
| ED50 | < 0.05 ng/ml. | |||||
| Specific activity | > 2*107units/mg. | |||||
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