| 包装: | 10ug |
| 市场价: | 4270元 |
| Gene ID: | 5228 | Accession #: | AAB30462 |
| Alternate Names: | Placenta Growth Factor-2, PGFL. | ||
| Source: | Escherichia Coli. | M.Wt: | 18.0 kDa |
| Appearance: | Lyophilized protein | Storage: | Store at -20°C |
| Formulation: | SSterile filtered and lyophilized with no additives. | ||
| Solubility: | Reconstitute the protein in sterile 20 mM acetic acid to a concentration of 0.1-1.0 μg/μl. The solution can then be diluted into other aqueous buffer and stored at 4℃ for 1 week or -20℃ for future use. | ||
| Shipping Condition: | Blue ice. | Handling: | Centrifuge the vial prior to opening. |
| Usage: | For Research Use Only! Not to be used in humans. | ||
Placenta Growth Factor-2 (PLGF-2) is an angiogenic factor produced in umbilical vein endothelial cells and placenta. PLGF-2 plays important roles in angiogenesis and endothelial cell growth. PLGF-2 signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. PLGF-2 also signals through Neuropilin (NP-1) in a heparin-dependent manner.
Recombinant human PLGF-2 is produced in E. coli as a homodimer containing 2 × 153 amino acids and having a total molecular mass of 36 kDa.
| The PLFG-2 is fully biologically active when compared with standards. Recombinant human PIGF-2 can bind to immobilized rh-sFlt-1 (100 ng/well) with linear range at 0.3-10 ng/ml. |
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