| 包装 | 价格(元) |
| 10ug | 电议 |
| 50ug | 电议 |
| 500ug | 电议 |
| 1mg | 电议 |
| Gene ID: | 10673 | Accession #: | Q9Y275 |
| Alternate Names: | human BAFF, h-BAFF, rh-BAFF, recombinant human BAFF, recombinant BAFF. | ||
| Source: | Escherichia Coli. | M.Wt: | 19.335 kDa |
| Appearance: | Lyophilized protein | Storage: | Store at -20°C |
| Formulation: | Lyophilized from 0.3× PBS, pH 7.5. | ||
| Solubility: | Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use. | ||
| Shipping Condition: | Gel pack. | Handling: | Centrifuge the vial prior to opening. |
| Usage: | For Research Use Only! Not to be used in humans. | ||
Human B cell activating factor (BAFF) is a 32 kDa transmembrane glycoprotein produced by T cells, macrophages, monocytes and dendritic cells. BAFF is a member of the TNF family of ligands and is involved in stimulation of B and T cell function. BAFF plays important roles in survival and maturation of peripheral B cells. BAFF signals through three different TNF receptors: TACI, BCMA and BAFF-R.
The human BAFF gene codes a 285 aa transmembrane protein containing a 46 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 218 amino acid extracellular domain. Recombinant human BAFF is a soluble protein containing 153 amino acid residues with a N-terminal His-tag (MW 19.335 kDa)
| Determined by the dose-dependent stimulation of IL-8 production by human PBMC. | ||||||
| ED50 | < 10 ng/ml. | |||||
| Please note: results may vary with PBMC donors. | ||||||
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