您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Qstatin
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Qstatin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Qstatin图片
CAS NO:902688-24-8
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
QStatin 是一种有效的选择性弧菌群体感应 (QS) 抑制剂,在不同的弧菌物种中显示出不同的 QS 抑制剂活性。QStatin 减弱了各种弧菌物种中代表性的 QS 调节表型,与 SmcR 中的假定配体结合口袋紧密结合,并改变蛋白质的灵活性,从而改变其转录调节活性。QStatin 可能是一种可用于水产养殖的可持续抗病毒剂。
Cas No.902688-24-8
Canonical SMILESO=S(N1N=CC=C1)(C2=CC=C(Br)S2)=O
分子式C7H5BrN2O2S2
分子量293.16
溶解度DMSO: 83.33 mg/mL (284.25 mM)
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

QStatin is a novel, potent, and selective Vibrio quorum sensing (QS) inhibitor, shows pan-QS inhibitor activity in diverse Vibrio species. QStatin attenuates representative QS-regulated phenotypes in various Vibrio speciesbinds tightly to a putative ligand-binding pocket in SmcR and changes the flexibility of the protein, thereby altering its transcription regulatory activity. QStatin may be a sustainable antivibriosis agent useful in aquacultures[1].

[1]. Kim BS, et al. QStatin, a Selective Inhibitor of Quorum Sensing in Vibrio Species. MBio. 2018 Jan 30;9(1). pii: e02262-17.