Zingibroside R1

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Zingibroside R1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

80930-74-1

包装与价格：

包装	价格(元)
1mg	电议
5mg	电议

产品介绍

Zingibroside R1 是一种三萜皂苷，分离自 Panax japonicas C. A. Meyer 根部，显示出优异的抗肿瘤作用以及抗血管生成活性。Zingibroside R1 具有一些抗 HIV-1 活性。Zingibroside R1 对 EAT 细胞的 2-脱氧-D-葡萄糖 (2-DG) 的摄取具有抑制作用(IC50=91.3 μM)。

Cas No.	80930-74-1
别名	姜状三七皂苷R1
Canonical SMILES	C[C@@]12C([C@@]3([H])[C@](C(O)=O)(CCC(C)(C)C3)CC2)=CC[C@]4([H])[C@@](C)(CC[C@H](O[C@@]5([H])[C@@H]([C@H]([C@H](O)[C@@H](C(O)=O)O5)O)O[C@]6([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)CO)C7(C)C)[C@@]7([H])CC[C@@]14C
分子式	C₄₂H₆₆O₁₄
分子量	794.97
溶解度	Soluble in DMSO
储存条件	4°C, protect from light
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	Zingibroside R1 is dammaranae-type triterpenoid saponin, isolated from rhizomes, taproots, and lateral roots of Panax japonicas C. A. Meyer, shows excellent anti-tumor effects as well as anti-angiogenic activity[1].Zingibroside R1 possesses some anti-HIV-1 activity.Zingibroside R1 has inhibitory effects on the 2-deoxy-D-glucose (2-DG) uptake by EAT cells (IC50=91.3 μM)[2]. IC50: 91.3 μM (2-DG uptake)[1] [1]. Yoshizaki K, et al. Saponins composition of rhizomes, taproots, and lateral roots of Satsuma-ninjin (Panax japonicus). Chem Pharm Bull (Tokyo). 2013;61(3):344-50. Epub 2012 Dec 28 [2]. Hasegawa H, et al. Inhibitory effect of some triterpenoid saponins on glucose transport in tumor cells and its application to in vitro cytotoxic and antiviral activities. Planta Med. 1994 Jun;60 (3):240-3.