Catalog No. | Product Name | Summary | Targets | CAS Number | Smiles |
A1902 | Z-VAD-FMK | Cell-permeable, irreversible pan-caspase inhibitor | Apoptosis|Caspase | 187389-52-2 | CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)OCC1=CC=CC=C1 |
A2576 | E-64 | Cysteine protease inhibitor,irriversible | Proteases|Cathepsin | 66701-25-5 | CC(C)CC(C(=O)NCCCCN=C(N)N)NC(=O)C1C(O1)C(=O)O |
A2585 | MG-132 | Proteasome inhibitor, Cell permeable, reversible | Ubiquitination/ Proteasome|Proteasome | 133407-82-6 | CC(C)CC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1 |
A3935 | WEHI-539 | Bcl-xL inhibitor,potent and selective | Apoptosis|Bcl-xL | 1431866-33-9 | C1CC2=C(C=C(C=C2)C3=NC(=C(S3)CCCOC4=CC=C(C=C4)CN)C(=O)O)C(=NNC5=NC6=CC=CC=C6S5)C1 |
A4234 | TW-37 | Bcl-2 inhibitor, inhibits Bcl-2,Bcl-XL and Mcl-1 | Apoptosis|Bcl-2 Family | 877877-35-5 | CC(C)C1=CC=CC=C1CC2=C(C(=C(C(=C2)C(=O)NC3=CC=C(C=C3)S(=O)(=O)C4=CC=CC=C4C(C)(C)C)O)O)O |
A8329 | R428 | Selective Axl inhibitor | Tyrosine Kinase|Axl | 1037624-75-1 | C1CCN(C1)C2CCC3=C(CC2)C=C(C=C3)NC4=NN(C(=N4)N)C5=NN=C6C(=C5)CCCC7=CC=CC=C76 |
A8717 | THZ2 | CDK7 inhibitor | Cell Cycle/Checkpoint|Cyclin-Dependent Kinases | 1604810-84-5 | CN(C/C([H])=C([H])/C(O)=N/C1=CC=CC(/C(O)=N/C2=CC(NC3=NC=C(Cl)C(C4=CNC5=CC=CC=C45)=N3)=CC=C2)=C1)C |
A8737 | S63845 | MCL1 inhibitor | Apoptosis|Bcl-2 Family | 1799633-27-4 | OC([C@@H](OC1=NC=NC2=C1C(C3=C(C)C(Cl)=C(OCCN4CCN(C)CC4)C=C3)=C(C5=CC=C(F)O5)S2)CC6=CC=CC=C6OCC7=CC=NN7CC(F)(F)F)=O |