NHS-12-Biotin

立即咨询

NHS-12-Biotin

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

包装与价格：

包装	价格(元)
100mg	电议
1g	电议

产品介绍

化学性质

Storage	Store at -20°C
M.Wt	539.64
Formula	C₂₄H₃₇N₅O₇S
Solubility	≥20.65 mg/mL in EtOH; ≥23.15 mg/mL in H2O; ≥44.5 mg/mL in DMSO
Chemical Name	2,5-dioxopyrrolidin-1-yl 4-(6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)butanoate
Canonical SMILES	O=C1N[C@@]([H])([C@]([H])(CS2)N1)[C@@H]2CCCCC(NCCCCCC(NCCCC(ON3C(CCC3=O)=O)=O)=O)=O
运输条件	蓝冰运输或根据您的需求运输。
一般建议	为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。

描述

NHS-12-Biotin is a derivative of D-biotin, a amine-reactive biotinylation agent, that contains a spacer arm off the valeric acid side chain of D-biotin with an NHS ester group at its end. The NHS ester group at the end of NHS-12-Biotin covalently binds to amine groups in proteins and other molecules forming a stable amide linkage and releasing the NHS group. NHS-12-Biotin has a greater length between a covalently modified molecule and the bicyclic biotin rings than NHS-LC-Biotin, which provides the avidin or streptavidin probes a greater opportunity to reach the binding sites deeply buried inside the surface plane of proteins. NHS-12-Biotin is insoluble in aqueous environments requiring the dissolution of organic solvents prior to the addition to a buffered reaction.