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Levoleucovorin Calcium
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Levoleucovorin Calcium图片
CAS NO:80433-71-2
包装:10mg
市场价:546元

产品介绍
Levoleucovorin Calcium (Calcium levofolinate) 是 Leuvorin Calcium 的左旋异构体,具有抗肿瘤作用。 Levoleucovorin Calcium 也是 5-氟尿嘧啶对癌症的细胞毒性的增强剂。
Cas No.80433-71-2
别名左亚叶酸钙; Calcium levofolinate; CL307782
化学名calcium;(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate
Canonical SMILESC1C(N(C2=C(N1)NC(=NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Ca+2]
分子式C20H21N7O7.Ca
分子量511.5
溶解度Water: 0.3 mg/ml
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Levoleucovorin calcium is the calcium salt of Levoleucovorin, which is the enantiomerically active form of folinic acid.IC50 value: Target: Levoleucovorin is used to treat or prevent toxic effects of methotrexate in people who have received methotrexate to treat bone cancer. Levoleucovorin is also used in combination chemotherapy with fluorouracil (5-FU) to treat colorectal cancer that has spread to other parts of the body. This medicine only treats the symptoms of colorectal cancer and does not treat the cancer itself.

References:
[1]. Levomefolic acid. From Wikipedia, the free encyclopedia