Taurocholic Acid (sodium salt) (Sodium taurocholate; N-Choloyltaurine sodium) 具有显着的生物活性作用,例如通过上调 VEGF-A 表达抑制肝动脉结扎诱导的胆道损伤的潜力。
Cas No. | 145-42-6 |
别名 | 牛磺胆酸钠,Sodium taurocholate; N-Choloyltaurine sodium |
Canonical SMILES | O[C@@H]1C[C@]2([H])C[C@H](O)CC[C@]2(C)[C@]3([H])[C@]1([H])[C@@](CC[C@]4([H])[C@@H](CCC(NCCS([O-])(=O)=O)=O)C)([H])[C@]4(C)[C@@H](O)C3.[Na+] |
分子式 | C26H45NO7S•Na |
分子量 | 537.7 |
溶解度 | DMF: 25 mg/ml,DMSO: 20 mg/ml,Ethanol: 2 mg/ml,PBS (pH 7.2): 3 mg/ml |
储存条件 | Store at 0-6°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Taurocholic acid (TCA) is a taurine-conjugated form of the primary bile acid cholic acid . Serum levels of TCA are decreased in patients with Crohn's disease and those with ulcerative colitis with no extraintestinal manifestations, but are increased in patients with ulcerative colitis accompanied by hepatobiliary disease. |