Chelidonine 是一种异喹啉生物碱，可从 Chelidonium majus L. 中分离得到。
| Cas No. | 476-32-4 |
| 别名 | 白屈菜碱 |
| Canonical SMILES | CN1CC2=C(C=CC3=C2OCO3)[C@@]4([H])[C@@H](O)CC5=CC6=C(OCO6)C=C5[C@]41[H] |
| 分子式 | C20H19NO5 |
| 分子量 | 353.4 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Chelidonine is a benzophenanthridine alkaloid that has been isolated from C. majus. It induces Bcl-2- and caspase-dependent apoptosis in HepG2 human liver carcinoma cells with an LC50 value of 12 µM and in Jurkat human T cells when used at a concentration of 1 µM. Chelidonine also downregulates hTERT expression in HepG2 cells, reduces telomerase activity, and induces cell senescence. |
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