2'-O-甲基鸟苷是在 tRNA 鸟苷-2'-O-甲基转移酶的作用下在 tRNA 中产生的修饰核苷。
| Cas No. | 2140-71-8 |
| 别名 | 2'-甲氧基鸟苷 |
| Canonical SMILES | O=C1C2=C(N([C@H]3[C@H](OC)[C@H](O)[C@@H](CO)O3)C=N2)N=C(N)N1 |
| 分子式 | C11H15N5O5 |
| 分子量 | 297.3 |
| 溶解度 | 0.1 M HCl: 10 mg/ml,DMF: 50 µ g/ml,DMSO: 12 mg/ml,Ethanol: 50 µ g/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 2'-O-Methylguanosine is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2'-O-methyltransferase, using S-adenosyl-L-methionine as a substrate. Through its interaction with other modified nucleosides, 2'-O-methylguanosine is thought to stabilize the structure of the tRNA. 2'-O-Methylguanosine can also be found in rRNA. Normal and modified nucleosides, including 2'-O-methylguanosine, have been shown to be secreted by a natural suppressor cell line and induce apoptosis in K562/Molt4 target cells. |
m.cnreagent.com