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D-Pinitol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
D-Pinitol图片
CAS NO:10284-63-6
包装:20mg
市场价:2184元

产品介绍
D-松醇 (3-O-Methyl-D-chiro-inositol) 是一种天然化合物,存在于几种植物中,如松科和豆科植物。
Cas No.10284-63-6
别名D-松醇,3-O-Methyl-D-chiro-inositol
化学名(1S,2S,4S,5R)-6-methoxycyclohexane-1,2,3,4,5-pentol
Canonical SMILESCOC1C(C(C(C(C1O)O)O)O)O
分子式C7H14O6
分子量194.18
溶解度DMF: 5 mg/ml,DMSO: 10 mg/ml,Ethanol: partially soluble,PBS (pH 7.2): 5 mg/ml
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

D-pinitol (3-O-Methyl-D-chiro-inositol) is a natural compound presented in several plants, like Pinaceae and Leguminosae plants. D-pinitol exerts hypoglycemic activity and protective effects in the cardiovascular system[1][2].

D-pinitol promotes apoptosis in MCF-7 cells via induction of p53 and Bax and inhibition of Bcl-2 and NF-κB[3].

References:
[1]. Gao Y, et al. Effects of D-Pinitol on Insulin Resistance through the PI3K/Akt Signaling Pathway in Type 2Diabetes Mellitus Rats. J Agric Food Chem. 2015 Jul 8;63(26):6019-26.
[2]. Moreira LN, et al. Activation of eNOS by D-pinitol Induces an Endothelium-Dependent Vasodilatation in MouseMesenteric Artery. Front Pharmacol. 2018 May 22;9:528.
[3]. Rengarajan T, et al. D-pinitol promotes apoptosis in MCF-7 cells via induction of p53 and Bax and inhibition of Bcl-2 and NF-κB. Asian Pac J Cancer Prev. 2014;15(4):1757-62.