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D-Mannoheptulose
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
D-Mannoheptulose图片
CAS NO:3615-44-9
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
D-甘露庚酮糖是鳄梨中一种主要的非结构碳水化合物。
Cas No.3615-44-9
别名D-甘露庚酮糖
Canonical SMILESOC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)C(CO)=O
分子式C7H14O7
分子量210.2
溶解度DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

D-Glucose is phosphorylated by glucokinase and three tissue-specific hexokinases to produce glucose-6-phosphate in humans. D-Mannoheptulose is a heptose that inhibits glucokinases and hexokinases from diverse organisms through competition with D-glucose (Ki = 0.25 mM). It blocks glucose oxidation and glucose-mediated insulin release from pancreatic islet cells. D-Mannoheptulose prevents the conversion of glucose to glucose-6-phosphate that can mediate the activation of the carbohydrate response element binding protein. By blocking glucose phosphorylation, D-mannoheptulose causes transient hyperglycemia in dogs when given at 1 g/kg but not at 8 mg/kg, although postprandial energy expenditure is increased at the lower dose.