您好，欢迎来到试剂仪器网！ [登录] [免费注册]
试剂仪器网
发布求购
位置：首页 > 产品库 > Verinurad
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
Verinurad
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Verinurad图片
CAS NO:1352792-74-5
包装与价格：
包装价格(元)
5mg电议
10mg电议
50mg电议

产品介绍
Verinurad (RDEA3170) 是一种高效且特异性的 URAT1 抑制剂，IC50 为 25 nM。
Cas No.1352792-74-5
别名维立诺雷; RDEA3170
Canonical SMILESCC(C)(SC1=C(C2=C3C=CC=CC3=C(C#N)C=C2)C=NC=C1)C(O)=O
分子式C20H16N2O2S
分子量348.42
溶解度DMSO : ≥ 30 mg/mL (86.10 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Verinurad is an urate transporter inhibitor with EC50 value of 0.05 uM.IC50 value: 0.05 uM (EC50)Target: urate transporterVerinurad is useful in the modulation of blood or serum uric acid levels, reducing serum uric acid levels in a human.

References:
[1]. Yeh Li-Tain, et al. 3,4-Di-substituted pyridine compound, methods of use and compositions comprising the same. From PCT Int. Appl. (2013), WO 2013067425 A1 20130510.
[2]. Ouk, Samedy, et al. Thioacetate compounds as URAT-1 agonists and their preparation, compositions and methods of use. From PCT Int. Appl. (2011), WO 2011159839 A2 20111222.