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D-Ornithine lactam
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
D-Ornithine lactam图片
CAS NO:88763-76-2
包装与价格:
包装价格(元)
50mg电议
100mg电议
250mg电议
500mg电议

产品介绍
A building block
Cas No.88763-76-2
别名R-3-氨基-2-哌啶酮
Canonical SMILESN[C@H]1C(NCCC1)=O
分子式C5H10N2O
分子量114.1
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

D-Ornithine lactam is a building block.1,2It has been used in the synthesis of hepatitis C virus (HCV) non-structural protein 5B (NS5B) inhibitors, as well as αVβ3 integrin receptor antagonists.

1.Li, P., Dorsch, W., Lauffer, D.J., et al.Discovery of novel allosteric HCV NS5B inhibitors. 2. Lactam-containing thiophene carboxylatesACS Med. Chem. Lett.8(2)251-255(2017) 2.Kubota, D., Ishikawa, M., Ishikawa, M., et al.Tricyclic pharmacophore-based molecules as novel integrin ɑvβ3 antagonists. Part IV: Preliminary control of ɑvβ3 selectivity by meta-oriented substitutionBioorg. Med. Chem.14(12)4158-4181(2006)