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KRAS G12C inhibitor 5
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
KRAS G12C inhibitor 5图片
CAS NO:2158297-63-1
包装与价格:
包装价格(元)
250mg电议
500mg电议

产品介绍
KRASG12Cinhibitor5是一种KRasG12C抑制剂,详细信息请参考专利文献WO2017201161A1中的化合物147。
Cas No.2158297-63-1
Canonical SMILESN#CC[C@@H]1N(C(C=C)=O)CCN(C2=C3C(CN(C4=C5C=CC=CC5=CC=C4)CC3)=NC(OC[C@H]6N(C)CCC6)=N2)C1
分子式C32H37N7O2
分子量551.68
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

KRAS G12C inhibitor 5 is a KRas G12C inhibitor extracted from patent WO2017201161A1, Compound example 147[1].

Kirsten Rat Sarcoma 2 Viral Oncogene Homolog (KRas) is a small GTPase and a member of the Ras family of oncogenes. KRas serves a molecular switch cycling between inactive (GDP -bound) and active (GTP -bound) states to transduce upstream cellular signals received from multiple tyrosine kinases to downstream effectors to regulate a wide variety of processes, including cellular proliferation[1].

[1]. John P. Fischer, et al. Kras g12c inhibitors. WO2017201161A1.