IL-3,human recombinant

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

包装与价格：

包装	价格(元)
10ug	电议
50ug	电议
1mg	电议

产品介绍

描述

Gene ID:	3562	Accession #:	P08700
Alternate Names:	IL3, MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor, IL-3, MGC79398, MGC79399.
Source:	Escherichia Coli.	M.Wt:	15.0 kDa
Appearance:	Lyophilized protein	Storage:	Store at -20°C
Formulation:	Sterile filtered and lyophilized with no additives.
Solubility:	Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4℃ for 1 week or -20℃ for future use.
Shipping Condition:	Blue ice.	Handling:	Centrifuge the vial prior to opening.
Usage:	For Research Use Only! Not to be used in humans.

资料参考

Interleukin 3 (IL-3) is a pleiotropic cytokine produced by activated T cells, mast cells and eosinophils, and stimulates the proliferation and differentiation of pluripotent hematopoietic stem cells, committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Also, IL-3 affects the functional activity of basophils, eosinophils, mature mast cells and macrophages. IL-3 enhances thrombopoiesis, phagocytosis, and antibody-mediated cellular cytotoxicity.

The human IL-3 cDNA encodes a 152 aa protein. Human and mouse IL-3 share only 29% sequence identity at the amino acid level. IL-3 is highly species-specific and human IL-3 does not show activity on murine cells. Recombinant human IL-3 is a 15.0 kDa protein containing 133 amino acid residues.

生物活性

Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells.
ED50	< 0.1 ng/ml.
Specific activity	> 1*10⁷units/mg.