GM-CSF,human recombinant

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

包装与价格：

包装	价格(元)
10ug	电议
100ug	电议
1mg	电议

产品介绍

描述

Gene ID:	1437	Accession #:	P04141
Alternate Names:	CSF2, human GM-CSF, GM-CSF,GMCSF, GM CSF, h-GM-CSF, rh-GM-CSF, recombinant human GM-CSF, recombinant GM-CSF.
Source:	Escherichia Coli.	M.Wt:	14.6 kDa
Appearance:	Lyophilized protein	Storage:	Store at -20°C
Formulation:	Lyophilized from 10 mM Sodium Citrate, pH 3.5.
Solubility:	Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4℃ for 1 week or -20℃ for future use.
Shipping Condition:	Gel pack.	Handling:	Centrifuge the vial prior to opening.
Usage:	For Research Use Only! Not to be used in humans.

资料参考

Granulocyte Macrophage Colony stimulating Factor (GM-CSF) is a cytokine that stimulates the colony formation of granulocyte-macrophage progenitors. GM-CSF is a pleiotropic cytokine and a member of endogenous cytokine family of the hematopoietic system. GM-CSF is mainly produced by activated T cells, B cells, macrophages and mast cells. GM-CSF plays an important role in stimulating the survival, proliferation, differentiation and activation of hematopoietic cells such as granulocytes and monocytes, basophiles and eosonophoiles, neutrophiles, erythroid cells, megakaryocytes and T cells.

Human GM-CSF is a 144 amino acids, 22kDa glycoprotein. Human and mouse GM-CSF are species specific and exhibit no cross-species reactivity. However, human GM-CSF is active on canine and feline cells. Recombinant human GM-CSF is a 14.6 kDa globular protein containing 128 amino acid residues.

生物活性

Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells.
ED₅₀	< 0.1 ng/ml.
Specific activity	> 1*10⁷units/mg.