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IL-1beta,human recombinant
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
IL-1beta,human recombinant图片
包装与价格:
包装价格(元)
10ug电议
50ug电议

产品介绍

描述

Gene ID:3553Accession #:P01584
Alternate Names:Human IL-1beta, IL-1beta, IL1beta, IL 1beta, h- IL-1beta, rh-IL-1beta, recombinant human IL-1beta, recombinant IL-1beta, IL, interluekin.
Source:Escherichia Coli.M.Wt:17.0 kDa
Appearance:Lyophilized proteinStorage:Store at -20°C
Formulation:Lyophilized with no additives.
Solubility:Reconstitute in water to a concentration of 0.1-1 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4℃ for 1 week or -20℃ for future use.
Shipping Condition:Gel pack.Handling:Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.

资料参考

Interleukin 1 beta (IL-1β) is a proinflammatory cytokine and is produced by activated macrophages, monocytes, keratinocytes and other epithelial cells. Both IL-1α and IL-1β bind to the same receptor and have similar biological properties, which includes the stimulation of thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, mitogenic fibroblast growth factor (FGF)-like activity, and the release of prostaglandin and collagenase from synovial cells. However, IL-1β is a secreted cytokine, whereas IL-1α is predominantly a cell-associated cytokine. 

The human IL-1β cDNA encodes a 269 aa precursor, which is cleaved intracellularly by the cysteine protease IL-1β-converting enzyme (Caspase-1/ICE) to produce the 153 aa active cytokine. Recombinant human IL-1β is a 17.0 kDa protein containing 153 amino acid residues.

生物活性

Determined by the dose-dependent stimulation of thymidine uptake by murine C3H/HeJ thymocytes.
ED50< 0.1 ng/ml.     
Specific activity> 1*107units/mg.