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IL-10,human recombinant protein
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
IL-10,human recombinant protein图片
包装与价格：
包装价格(元)
10ug电议
50ug电议
1mg电议

产品介绍

描述

Gene ID:3586Accession #:P22301
Alternate Names:Human IL-10, IL-10, IL10, IL 10, h-IL-10, rh-IL-10, recombinant human IL-10, recombinant IL-10, IL, interluekin.
Source:Escherichia Coli.M.Wt:18.6 kDa
Appearance:Lyophilized proteinStorage:Store at -20°C
Formulation:Lyophilized from PBS.
Solubility:Reconstitute in H2O to a concentration of 0.1-1.0 μg/μl. The solution can then be diluted into other aqueous buffers and stored at 4℃ for 1 week or -20℃ for future use.
Shipping Condition:Gel pack.Handling:Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.

资料参考

Interleukin-10 (IL-10) is an immunosuppressive cytokine produced by macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the synthesis of proinflammatory cytokines such as IL-1 and TNF-α and proliferation of T cells. IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-kappa B activity and is involved in regulating the JAK-STAT signaling pathway. IL-10 plays an important role in the control of viral infections and allergic and autoimmune inflammation.

 The human IL-10 cDNA encodes a 178 aa protein with a 18 aa signal sequence. Human IL-10 is active on murine cells, but murine IL-10 is inactive on human cells. Recombinant human IL-10 is an 18.6 kDa protein containing 161 amino acid residues.

生物活性

Determined by the dose-dependent co-stimulation (with murine IL-4) of MC/9 cells.
ED50< 2 ng/ml.     
Specific activity> 5*105units/mg.