Catalog No. | Product Name | Summary | Targets | CAS Number | Smiles |
A1902 | Z-VAD-FMK | Cell-permeable, irreversible pan-caspase inhibitor | Caspase | 187389-52-2 | CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)OCC1=CC=CC=C1 |
A2005 | Nutlin-3b | MDM2/p53 inhibitor | MDM2 | 675576-97-3 | CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl |
A3762 | RG7112 | MDM2 inhibitor, first clinical | MDM2 | 939981-39-2 | CCOC1=C(C=CC(=C1)C(C)(C)C)C2=NC(C(N2C(=O)N3CCN(CC3)CCCS(=O)(=O)C)(C)C4=CC=C(C=C4)Cl)(C)C5=CC=C(C=C5)Cl |
A4213 | Necrostatin-1 | RIP1 inhibitor | TNF-α | 4311-88-0 | CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32 |
A4484 | PRIMA-1MET | Restore mutant p53 activity, induce BAX and PUMA | p53 | 5291-32-7 | COCC1(C(=O)C2CCN1CC2)CO |
A8177 | PAC-1 | Procaspase-3 activator | Caspase | 315183-21-2 | C=CCC1=CC=CC(=CNNC(=O)CN2CCN(CC2)CC3=CC=CC=C3)C1=O |
A8223 | CID 2011756 | PKD inhibitor | Protein Ser/Thr Phosphatases | 638156-11-3 | C1COCCN1CC2=CC=C(C=C2)NC(=O)C3=CC=C(O3)C4=CC(=CC=C4)Cl |
B3232 | Z-IETD-FMK | Caspase-8 inhibitor | Caspase | 210344-98-2 | CCC(C)C(C(=O)NC(CCC(=O)OC)C(=O)NC(C(C)O)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)OCC1=CC=CC=C1 |