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N6-Ethyladenosine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
N6-Ethyladenosine图片
CAS NO:14357-08-5
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
10mg电议
50mg电议

产品介绍
N6-Ethyladenosine是一种腺苷衍生物，为腺苷受体(Adenosinereceptor)激动剂，对hA1AR和hA3AR的Ki值分别为4.9和4.7nM。
Cas No.14357-08-5
Canonical SMILESOC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2N=CN=C3NCC)O1)O)O
分子式C12H17N5O4
分子量295.29
溶解度DMSO : ≥ 83.33 mg/mL (282.20 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

N6-Ethyladenosine is an adenosine derivative, acts as a Adenosine receptor agonist, with Kis of 4.9 and 4.7 nM for hA1AR and hA3AR, respectively[1]. Ki: 4.9 nM (hA1AR), 4.7 nM (hA3AR)[1]

N6-Ethyladenosine (Compound 28) exhibits more selectivity at hA1AR and hA3AR over hA2AR (Ki, 8900±770 nM)[1].

[1]. Kimand SK, et al. Three-dimensional quantitative structure-activity relationship of nucleosides acting at the A3 adenosine receptor: analysis of binding and relative efficacy. J Chem Inf Model. 2007 May-Jun;47(3):1225-33. Epub 2007 Mar 6.