化学性质
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 326.42 |
Cas No. | 908007-17-0 |
Formula | C13H22N6O2S |
Solubility | ≥32.6 mg/mL in DMSO; insoluble in H2O; ≥2.51 mg/mL in EtOH with ultrasonic |
Chemical Name | N-(3-azidopropyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide |
Canonical SMILES | O=C1N[C@@]([H])(CS[C@H]2CCCCC(NCCCN=[N+]=[N-])=O)[C@]2([H])N1 |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
资料参考
Biotin azide reacts with the terminal alkynes via a copper-catalyzed click reaction, including biomolecules containing alkyne groups through azide-alkyne cycloaddition. Biotin and biotin derivatives can be readily conjugated to various biomolecules through the well-known click chemistry and subsequently detected with streptavidin, avidin or NeutrAvidin biotin-binding protein. Biotin azide can be used to prepare various biotinylated conjugates via Click Chemistry. Click chemistry contains a class of chemical reactions that use bio-orthogonal or biologically unique moieties to label and detect the molecule in mild and aqueous conditions. This reagent allows labeling of various alkynylated molecules, such as DNA, oligonucleotides, and proteins with biotin. Biotin binding to avidin or streptavidin could be used in downstream affinity applications for the isolation of biotinylated molecules or their binding with streptavidin conjugates [1].
Reference:
[1] Bruckman M A, Czapar A E, VanMeter A, et al. Tobacco mosaic virus-based protein nanoparticles and nanorods for chemotherapy delivery targeting breast cancer[J]. Journal of Controlled Release, 2016, 231: 103-113.