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Roseoflavin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Roseoflavin图片
CAS NO:51093-55-1
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍

化学性质

Physical AppearanceA crystalline solid
StorageStore at -20°C
M.Wt405.41
Cas No.51093-55-1
FormulaC18H23N5O6
Solubility≥24.25 mg/mL in DMSO
Chemical Name8-(dimethylamino)-7-methyl-10-((2S,3S,4R)-2,3,4,5-tetrahydroxypentyl)benzo[g]pteridine-2,4(3H,10H)-dione
Canonical SMILESO=C(C1=NC2=CC(C)=C(N(C)C)C=C2N(C[C@H](O)[C@H](O)[C@H](O)CO)C1=N3)NC3=O
运输条件蓝冰运输或根据您的需求运输。
一般建议为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。

资料参考

Roseoflavin is an analog of flavin mononucleotide (FMN) and riboflavin that is synthesized by the soil bacterium S. davawensis and possesses antimicrobial activity[1].

Roseoflavin has been shown to bind directly to FMN riboswitch aptamers (KD = ~100 nM), downregulating the expression of genes responsible for the synthesis and transport of riboflavin[2].

References:

[1]. Langer S, Hashimoto M, Hobl B, et al. Flavoproteins are potential targets for the antibiotic roseoflavin in Escherichia coli. Journal of Bacteriology, 2013, 195(18): 4037-4045.

[2]. Lee E R, Blount K F, Breaker R R. Roseoflavin is a natural antibacterial compound that binds to FMN riboswitches and regulates gene expression. RNA Biol, 2009, 6(2): 187-194.