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N-butyryl-L-Homoserine lactone
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
N-butyryl-L-Homoserine lactone图片
CAS NO:67605-85-0
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍

化学性质

Physical AppearanceA crystalline solid
StorageStore at -20°C
M.Wt171.19
Cas No.67605-85-0
FormulaC8H13NO3
Solubility≥43.4 mg/mL in DMSO; ≥53.6 mg/mL in EtOH; ≥43.6 mg/mL in H2O
Chemical Name(S)-N-(2-oxotetrahydrofuran-3-yl)butyramide
Canonical SMILESCCCC(N[C@H]1CCOC1=O)=O
运输条件蓝冰运输或根据您的需求运输。
一般建议为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。

资料参考

N-butyryl-L-Homoserine lactone is a small diffusible signaling molecule involved in quorum sensing (QS) [1].

QS is a way of cell-to-cell communication that utilizes diffusible signaling molecules sensed by the population to determine population density, thus coordinating gene regulation in response to population density. The various potential applications of N-butyryl-L-Homoserine lactone includes virulence regulation, infection prevention, and biofilm formation [1]. In addition, N-butyryl-L-Homoserine lactone may also act as an elicitor from bacteria in plant [2].

In the excised root cells of Arabidopsis plants, 10 μM N-butyryl-L-Homoserine lactone induced a transient and immediate increase in the cytosolic free Ca2+ concentration ([Ca2+]cyt), the highest level of which was 0.4 μM, approximately 2-fold higher than the basal level. Pretreatments of verapamil, La3+ or ethylene glycol tetraacetic acid (EGTA) reversed the increase in [Ca2+]cyt triggered by N-butyryl-L-Homoserine lactone, whilst it remained unaffected by pretreatment with Li+, indicating that the Ca2+ contributing to the increase in [Ca2+]cyt was transferred from the extracellular medium via the plasma membrane Ca2+ channels but not from the intracellular Ca2+ storage. Furthermore, N-butyryl-L-Homoserine lactone significantly increased the transmembrane Ca2+ current [2].

References:

[1]. Wu D, Huang W, Duan Q, et al. Sodium houttuyfonate affects production of N-acyl homoserine lactone and quorum sensing-regulated genes expression in Pseudomonas aeruginosa. Frontiers in Microbiology, 2014, 5(635): 1-9.

[2]. Song S, Jia Z, Xu J, et al. N-butyryl-homoserine lactone, a bacterial quorum-sensing signaling molecule, induces intracellular calcium elevation in Arabidopsis root cells. Biochemical and Biophysical Research Communications, 2011, 414(2): 355-360.