CMPF

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CMPF

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

86879-39-2

包装与价格：

包装	价格(元)
500ug	电议
1mg	电议
5mg	电议
10mg	电议

产品介绍

化学性质

Physical Appearance	A crystalline solid
Storage	Store at -20°C
M.Wt	240.25
Cas No.	86879-39-2
Formula	C₁₂H₁₆O₅
Solubility	insoluble in H2O; ≥48.4 mg/mL in EtOH; ≥49.4 mg/mL in DMSO
Chemical Name	2-(2-carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic acid
Canonical SMILES	CCCC1=C(C)C(C(O)=O)=C(CCC(O)=O)O1
运输条件	蓝冰运输或根据您的需求运输。
一般建议	为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。

资料参考

CMPF is an endogenous metabolite of furan fatty acids. CMPF is highly bound to albumin. Its main role is to inhibit cell transport and subsequent deiodination of thyroxine (T4)[1].

CMPF can effectively replace the competitive T4 binding molecules in albumin and play a role by indirectly binding albumin. And CMPF can inhibit the binding of T4 and albumin by increasing the serum concentration of competitive binding molecules such as oleic acid[2].

References:

[1]. Lim C, Bernard B F, De Jong M, et al. A furan fatty acid and indoxyl sulfate are the putative inhibitors of thyroxine hepatocyte transport in uremia. The Journal of Clinical Endocrinology and Metabolism, 1993, 76(2): 318-324.

[2]. Lim C F, Stockigt J R, Curtis A J, et al. A naturally occuring furan fatty acid enhances drug inhibition of thyroxine binding in serum. Metabolism, 1993, 42(11): 1468-1474.