Desription: PfDHODH-IN-2, a dihydrothiophenone derivative (Compound 11), is a Novel and potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor with an IC50 of 1.11 μM. PfDHODH-IN-2 acts as an antimalarial agent and can be used for the research of malaria.

References: [1]. Minghao Xu, et al. Novel selective and potent inhibitors of malaria parasite dihydroorotate dehydrogenase: discovery and optimization of dihydrothiophenone derivatives. J Med Chem. 2013 Oct 24;56(20):7911-24.

纯度：≥98%

CAS： 425629-94-3